Skin Disorders and Treatment

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Bowen's Disease

Bowen's Disease is characterized by a precancerous, slow growing skin malignancy. The major symptom is a red-brown, scaly or crusted patch on the skin which resembles psoriasis or dermatitis. It may occur on any part of the skin or in the mucous membranes. Bowen's disease is most common in sun-exposed areas but may arise at any location. The lesion can be solitary or multiple. Bowen's disease is most common in sun-exposed areas but may arise at any location. The lesion can be solitary or multiple. Bowen's disease is most often seen in people in their 60s and 70s, and is about three times more common in women than men.  The commonest site is the lower leg, mainly in women. About a fifth of women with it have more than one patch.

Bowen's Disease Causes

A skin disease marked by scaly or thickened patches on the skin and often caused by prolonged exposure to arsenic. The patches often occur on sun-exposed areas of the skin and in older, white men. The wart virus that causes cervical cancer (HPV 16) is often found to be infecting SCC in situ. It is thought that infection with this virus is one of the reasons why two people may have the same amount of sun damage, but only one keeps getting skin cancers. The other factor that causes SCC in situ is arsenic, the same poison made famous by the play "Arsenic and Old Lace" and the Russian villain Rasputin.

Bowen's Disease Symptoms

1. It may occur at any age but is most after the age of 30 and after age of 60 its chances are maximum.
2. In this disease the dumps grows like wart that crusts and bleeds occasionally.
3. In brown's diseaesepersistent, scaly red patch with irregular borders that sometimes crusts or bleeds.
4. Occasionally they can develop into a true skin cancer, which will require surgical removal usually, under a local anesthetic.
5. Bowen's cells like to grow down hair pores. This tendency for "poral invasion" may give the extremely atypical/unusual cells of Bowen's access to the bloodstream, should they break through the basement membrane. The author believes that the possibility of invasion may be increased by time, trauma and previously failed treatments.

Bowen's Disease Treatment

Bowen disease is usually treated by simple excision. This is not a complex situation. This is a simple treatment and doctor can do it simply.

Radiotherapy treats Bowen's disease by using high- energy x-rays which destroy the abnormal cells while doing as little harm as possible to normal cells. It works well for Bowen's disease and may be useful in areas where surgery might be difficult or disfiguring.

In some cases a cream known as 5-fluorouracil (Efudix cream) may be used.  Photodynamic therapy is available in some clinics now: radiotherapy (X-ray treatment) is being used less often. Photodynamic therapy is a new form of treatment.  A chemical is applied to the skin that makes the cells in the patch of Bowen's disease sensitive to particular wavelengths of light. Curettage the lesion is scraped off the skin. It may also be used with cauterisation, where the skin is lightly burnt with and electric current. Recurrence is slightly more likely than with surgery.

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